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Metrology

Amount of substance

News and Updates

Blog Posts

George Caceres wears safety glasses and a lab coat as he looks at a plastic test tube he is holding.

Measuring Microplastics: To Solve the Problem, We Have to Understand and Measure It

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View from the back of a darkened movie theater shows the heads of the audience and a screen reading: Measurement in the Movies.

Measurement in the Movies

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Title card reads "A Scientific Christmas Tale" with the NIST logo in a wreath and flashing holiday lights.

A Scientific Christmas Tale

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Events

Projects and Programs

Advanced Mass Spectrometry Methods for Trace Detection

Ongoing
Ambient Ionization Mass Spectrometry (AI-MS) AI-MS remains a versatile field enabling direct analysis of samples in situ, requiring minimal or no sample preparation. These platforms are leveraged for the trace detection of organic and inorganic compounds, including, homemade and improvised

Ambient and Atmospheric Pressure Mass Spectrometry

Ongoing
Surface and Trace Chemical Analysis Group employs a range of commercial pneumatically-assisted electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI), and atmospheric pressure photoionization (APPI) sources for traditional mass spectrometric chemical analysis, identification
Photograph of gas cylinders

Audit of EPA Protocol Gas Suppliers

Ongoing
Protocol gas standards are employed in measurements made for compliance purposes; one of the major uses is for measurements of regulated gaseous species from stationary source emitters, i.e., stack gases. Many of these stationary sources are regulated through the Cap and Trade program; therefore
Image showing a variety of gas tanks with carbon dioxide

Carbon Dioxide Measurements and Reference Materials

Ongoing
CO 2 Reference Materials The Gas Sensing Metrology Group at NIST has a long history of providing reference materials to industry, monitoring communities, and academia. The program began in the 1970’s by developing an initial suite of CO2 primary standard mixtures (PSMs) to support the US Department

Publications

NIST Special Publication 260 NIST.SP.260-256 Certification of Standard Reference Material®s 3672a & 3673a: Organic Contaminants in Smokers' Urine (Frozen) & Organic Contaminants in Non-Smokers' Urine (Frozen)

Author(s)
Ashley Russell, Carolyn Burdette, Johanna Camara, Nathanael Heckert, Jennifer Hoguet, Kevin Huncik, Jared Ragland, Elena Wood
Standard Reference Material (SRM) 3672a Organic Contaminants in Smokers' Urine (Frozen) and SRM 3673a Organic Contaminants in Non-Smokers' Urine (Frozen) are

Certification of Standard Reference Material® 956e Electrolytes in Frozen Human Serum

Author(s)
Lee Yu, Steven Christopher, Regina Easley, Monique Johnson, Dennis Leber, Thomas Vetter, Jason Waters, Charles Barber, Karen Murphy, Laura Wood, Stephen Chin, Murli Narayan, Alexander Rhodes, Michael Nash
The National Institute of Standards and Technology (NIST) Standard Reference Material® (SRM®) 956e Electrolytes in Frozen Human Serum is intended for use in the

CCQM-P199b: Interlaboratory comparability study of SARS-CoV-2 RNA copy number quantification

Author(s)
Alison Devonshire, Eloise Busby, Gerwyn Jones, Denise O'Sullivan, Ana Fernandez-Gonzalez, Laura Hernandez-Hernandez, Xinhua Dai, Lianhua Dong, Chunyan Niu, Jie Xie, Xia Wang, Xiaoting Qiao, Xiang Fang, Clare Morris, Neil Almond, Megan Cleveland, Peter Vallone, Esther Castro Galván, Melina Pérez Urquiza, Mercedes Guadalupe Herrera López, Arifa Khan, Sandra Fuentes, Elsa Baumeister, John Emerson Leguizamon Guerrero, Sergio Luis Davila Gonzalez, Andres Felipe León Torres, Aurea Folgueras-Flatschart, Marcelo Neves de Medeiros, Antonio Marcos Saraiva, Roberto Becht Flatschart, Carla Divieto, Mattia Pegoraro, Massimo Zucco, Laura Revel, Marco Mazzara, Philippe Corbisier, Gerhard Buttinger, Young-Kyung Bae, Alexandra Bogožalec Košir, Mojca Milavec, Malcolm Hawkins, A. Pia Sanzone, Phattarapornn Morris, Sasithon Temisak, David Lynch, Jacob McLaughlin, Michael Forbes-Smith, Felicity Hall, Daniel Burke, Sachie Shibayama, Shin-ichiro Fujii, Megumi Kato, Samreen Falak, Rainer Macdonald, Andreas Kummrow, Andrey Komissarov, Sema Akyurek, Muslum Akgoz, Maxim Vonsky, Andrey Runov, Elena Kulyabina, Denis Rebrikov, Jim Huggett
RNA is the analyte targeted by nucleic acid amplification tests for SARS-CoV-2 virus, the causative agent of the COVID-19 pandemic. RNA concentration measured

Tools and Instruments

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